1,3-Dimethyluric acid (Standard)
Based on 1 Customer Validation
1,3-Dimethyluric acid Standard is the analytical standard of 1,3-Dimethyluric acid (HY-W014993). This product is intended for research and analytical applications. 1,3-Dimethyluric acid is a major metabolite of Theophylline (HY-B0809) in vivo. 1,3-Dimethyluric acid is an inhibitor of human organic anion transporter 1 (hOAT1) with an IC50 of 9.2 μM. 1,3-Dimethyluric acid inhibits hOAT1-mediated substrate uptake and transport through competitive binding. 1,3-Dimethyluric acid is also a component of urinary calculi. 1,3-Dimethyluric acid can be used in research on urolithiasis.
For research use only. We do not sell to patients.
- Purity : 99.16%
- CAS No.: 944-73-0
- Formula: C7H8N4O3
- Molecular Weight:196.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-W014993
1,3-Dimethyluric acidhOAT1 Inhibitor/Drug Metabolite -
HY-W008566
NorharmaneMAO Inhibitor -
HY-N0591
Dehydrocostus LactoneSesquiterpene -
HY-113327
1,3,7-Trimethyluric acidCaffeine Metabolite -
HY-B1505
AcefyllineAdenosine Receptor Antagonist -
HY-W008566R
Norharmane (Standard)MAO Inhibitor -
HY-B1505G
Acefylline (GMP)Adenosine Receptor Antagonist -
HY-B1505R
Acefylline (Standard)Analytical Standard -
HY-N0591R
Dehydrocostus Lactone (Standard)Standard of Dehydrocostus Lactone -
HY-113327R
1,3,7-Trimethyluric acid (Standard)Caffeine Metabolite -
HY-113327S
1,3,7-Trimethyluric acid-d9Stable Isotope
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 944-73-0
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Appearance Solid
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Molecular Weight 196.16
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Formula C7H8N4O3
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Color White to off-white
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SMILES
O=C(N1C)N(C)C2=C(NC(N2)=O)C1=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[5]. Kuroda Y, et al. Age-Associated Theophylline Metabolic Activity Corresponds to the Ratio of 1,3-Dimethyluric Acid to Theophylline in Mice. Biological & pharmaceutical bulletin. 2019;42(8):1423-1427. [Content Brief]
[7]. Tang-Liu DD, et al. Nonlinear theophylline elimination. Clin Pharmacol Ther. 1982 Mar;31(3):358-69.
[8]. Kuh HJ, et al. Nonlinear renal excretion of theophylline and its metabolites, 1-methyluric acid and 1,3-dimethyluric acid, in rats. Archives of pharmacal research. 1994 Apr;17(2):124-30. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1,3-Dimethyluric acid (Standard) Related Classifications
HY-W014993R Related Classifications
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