CSNK1G3/CK1g3
Completing the gamma subfamily, CK1γ3 (gene CSNK1G3) is a membrane-associated, lipid-modified CK1 isoform expressed prominently in brain and kidney. It phosphorylates the Wnt co-receptor LRP6 to potentiate canonical Wnt signaling and has been detected at the centrosome and in trafficking vesicles. In cultured cells CK1γ3 overexpression alters microtubule organization and cell adhesion, and it has been proposed to influence axon growth in neurons. Relative to CK1γ1 and CK1γ2, CK1γ3 is the least studied gamma isoform, with no firmly established disease phenotype, so recombinant CK1γ3 is mainly used to dissect isoform redundancy in membrane-proximal CK1 signaling.
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CSNK1G3/CK1g3 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
