country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-113482S

Copy Link Print Information

1β-Hydroxydeoxycholic acid-d₅

Name: 1β-Hydroxydeoxycholic acid-d5
Brand: MedChemExpress
SKU: HY-113482S
Price: 1100.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: 1β-OH-DCA-d₅)

1β-Hydroxydeoxycholic acid-d₅ (1β-OH-DCA-d₅) is the deuterated-labeled 1β-Hydroxydeoxycholic acid (HY-113482). 1β-Hydroxydeoxycholic acid (1β-OH-DCA) is an endogenous bile acid metabolite formed from deoxycholic acid via CYP3A-mediated 1β-hydroxylation. 1β-Hydroxydeoxycholic acid undergoes rapid metabolism in human hepatocytes, primarily through glycine conjugation to form G-1β-OH-DCA, with minor taurine conjugation and sulfation. The urinary ratio of 1β-Hydroxydeoxycholic acid to deoxycholic acid can be used as an endogenous biomarker for assessing CYP3A activity. 1β-Hydroxydeoxycholic acid can be used in metabolism-related research.

For research use only. We do not sell to patients.

Formula: C₂₄H₃₅D₅O₅
Molecular Weight:413.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

1β-Hydroxydeoxycholic acid-d₅ Chemical Structure

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

^[1]

CYP3A

All Endogenous Metabolite Isoforms :

All Cytochrome P450 Isoforms :

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 80434-32-8
Molecular Weight 413.60
Formula C₂₄H₃₅D₅O₅
SMILES

C[C@@]12[C@]3([H])[C@](CC[C@]1([H])C([2H])([2H])[C@](C([2H])([2H])[C@H]2O)([2H])O)([H])[C@@]4([H])[C@]([C@H](C3)O)([C@@](CC4)([H])[C@H](C)CCC(O)=O)C
Synonyms

1β-OH-DCA-d₅
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hayes MA, et al. CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity. Drug metabolism and disposition: the biological fate of chemicals. 2016 Sep;44(9):1480-9.

[2]. Ma Y, et al. Precision medication based on the evaluation of drug metabolizing enzyme and transporter functions. Precision clinical medicine. 2025 Mar;8(1):pbaf004.

[3]. Tremmel R, et al. Circulating biomarkers instead of genotyping to establish metabolizer phenotypes. Annual Review of Pharmacology and Toxicology. 2024 Jan 23;64(1):65-87.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
- Application
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

1β-Hydroxydeoxycholic acid-d5

All Endogenous Metabolite Isoforms

All Cytochrome P450 Isoforms

Biological Activity

Description

IC50 & Target

Application

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

1β-Hydroxydeoxycholic acid-d5 Related Classifications

HY-113482S Related Classifications

Bioz

Keywords

Your Recently Viewed Products

1β-Hydroxydeoxycholic acid-d₅

IC₅₀ & Target

1β-Hydroxydeoxycholic acid-d₅ Related Classifications