2-Hydroxybenzoyl-CoA lithium
Based on 1 Customer Validation
2-Hydroxybenzoyl-CoA (o-Hydroxybenzoyl-coenzyme A) lithium is a coenzyme A thioester of o-hydroxybenzoic acid and substrate for esterolysis. 2-Hydroxybenzoyl-CoA lithium serves as a substrate for studies of acyl-CoA formation, acyl transfer, and peptide bond formation reactions and enzymes.
For research use only. We do not sell to patients.
- Purity : 99.13%
- Formula: C28H40N7O18P3S·xLi
- Molecular Weight:887.64 (free acid)
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
2-Hydroxybenzoyl-CoA lithium undergoes esterolysis via phenolate-assisted water attack on the benzoyl moiety’s carbonyl carbon, with hydrolysis rate nearly constant over pH 9.6-12.1[1].
2-Hydroxybenzoyl-CoA lithium exists predominantly in an intramolecular adenyl-benzoyl complex under physiological conditions, which may contribute to acyl-CoA substrate specificity of acyl-CoA: amino acid N-acyltransferases[1].
2-Hydroxybenzoyl-CoA lithium has a characteristic ultraviolet absorption spectrum with a phenolate absorbance band that red shifts with increasing pH, exploitable for discontinuous enzymatic assays[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 887.64 (free acid)
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Formula C28H40N7O18P3S·xLi
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SMILES
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OP(O)(O)=O)[C@@H](COP(OP(OCC(C)([C@@H](O)C(NCCC(NCCSC(C4=CC=CC=C4O)=O)=O)=O)C)(O)=O)(O)=O)O3.[Li].[x]
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Synonyms
o-Hydroxybenzoyl-coenzyme A lithium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)