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Cat. No.: HY-W013675S

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2-Methoxyhydroquinone-d₃

2-Methoxyhydroquinone-d₃ is the deuterated-labeled 2-Methoxyhydroquinone (HY-W013675). 2-Methoxyhydroquinone is a phenolic compound that reduces TNF-α-induced production of chemokine (C-C motif) ligand 2 (CCL2) with an IC₅₀ value of 64.3 µM. 2-Methoxyhydroquinone is also a precursor in the synthesis of the Hsp90 inhibitor Geldanamycin (HY-15230).

For research use only. We do not sell to patients.

Formula: C₇H₅D₃O₃
Molecular Weight:143.16

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

2-Methoxyhydroquinone-d₃ Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
References
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Bioz

Biological Activity

Description

All HSP Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 824-46-4
Molecular Weight 143.16
Formula C₇H₅D₃O₃
SMILES

OC1=CC(OC([2H])([2H])[2H])=C(O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Houser KR, et al. Anti-inflammatory effects of methoxyphenolic compounds on human airway cells. J Inflamm (Lond). 2012 Mar 13;9:6. [Content Brief]

[2]. Qin HL, et al. Total synthesis of the Hsp90 inhibitor geldanamycin. Org Lett. 2008 Jun 19;10(12):2477-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
References

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2-Methoxyhydroquinone-d3

All HSP Isoforms