2-Pyrimidinecarboxylic acid
Based on 1 Customer Validation
2-Pyrimidinecarboxylic acid (2-Carboxy-Pyrimidine) is a nitrogen-containing heterocyclic carboxylic acid drug intermediate with antibacterial activity. 2-Pyrimidinecarboxylic acid potently inhibits the viability of Pseudomonas aeruginosa. 2-Pyrimidinecarboxylic acid can be used in research on bacterial infections.
For research use only. We do not sell to patients.
- Purity : 99.91%
- CAS No.: 31519-62-7
- Formula: C5H4N2O2
- Molecular Weight:124.10
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:DLD-1 colorectal adenocarcinoma cells
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Concentration:0.5, 0.75, 1, 10, 20, 50, 100, 200, 500, 750, 1000 μM
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Incubation Time:24 h
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Result:Caused a decrease in cell viability by approximately 5% at 20 μM, with an overall mild cytotoxicity.
Chemical Information
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CAS No. 31519-62-7
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Appearance Solid
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Molecular Weight 124.10
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Formula C5H4N2O2
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Color White to light yellow
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SMILES
O=C(O)C1=NC=CC=N1
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Synonyms
2-Carboxy-Pyrimidine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (805.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (285 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.0580 mL | 40.2901 mL | 80.5802 mL | 201.4504 mL |
| 5 mM | 1.6116 mL | 8.0580 mL | 16.1160 mL | 40.2901 mL | |
| 10 mM | 0.8058 mL | 4.0290 mL | 8.0580 mL | 20.1450 mL | |
| 15 mM | 0.5372 mL | 2.6860 mL | 5.3720 mL | 13.4300 mL | |
| 20 mM | 0.4029 mL | 2.0145 mL | 4.0290 mL | 10.0725 mL | |
| 25 mM | 0.3223 mL | 1.6116 mL | 3.2232 mL | 8.0580 mL | |
| 30 mM | 0.2686 mL | 1.3430 mL | 2.6860 mL | 6.7150 mL | |
| 40 mM | 0.2015 mL | 1.0073 mL | 2.0145 mL | 5.0363 mL | |
| 50 mM | 0.1612 mL | 0.8058 mL | 1.6116 mL | 4.0290 mL | |
| 60 mM | 0.1343 mL | 0.6715 mL | 1.3430 mL | 3.3575 mL | |
| 80 mM | 0.1007 mL | 0.5036 mL | 1.0073 mL | 2.5181 mL | |
| 100 mM | 0.0806 mL | 0.4029 mL | 0.8058 mL | 2.0145 mL |