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Cat. No.: HY-W588264

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3-Iodo-L-thyronine

Name: 3-Iodo-L-thyronine
Brand: MedChemExpress
SKU: HY-W588264
Price: 120.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: 3-Monoiodothyronine)

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Based on 1 Customer Validation

3-Iodo-L-thyronine (3-Monoiodothyronine) is an endogenous iodothyronine thyroid hormone metabolite. 3-Iodo-L-thyronine can be used for research on differentiated thyroid cancer.

For research use only. We do not sell to patients.

Purity : 99.79%
CAS No.: 10468-90-3
Formula: C₁₅H₁₄INO₄
Molecular Weight:399.18

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

3-Iodo-L-thyronine Chemical Structure

CAS No.: 10468-90-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

3-Iodo-L-thyronine (3-Monoiodothyronine) is an endogenous iodothyronine thyroid hormone metabolite. 3-Iodo-L-thyronine can be used for research on differentiated thyroid cancer^[1]^[2]^[3]^[4].

IC₅₀ & Target

^[1]

Human Endogenous Metabolite

All Endogenous Metabolite Isoforms :

In Vitro

Anti-cancerOthers

Anti-cancer

3-Iodo-L-thyronine is quantified by the validated LC-MS/MS method in Hep G2 cell lysate extracts with an LLOQ of 0.063 nM and LLOD of 0.031 nM^[3].

Others

3-Iodo-L-thyronine is quantified by the validated LC-MS/MS method in PCCL3 cell lysate extracts with an LLOQ of 0.050 nM and LLOD of 0.025 nM^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Endocrine Diseases

Chemical Information

CAS No. 10468-90-3
Appearance Solid
Molecular Weight 399.18
Formula C₁₅H₁₄INO₄
Color Off-white to light brown
SMILES

IC(C=C(C=C1)C[C@H](N)C(O)=O)=C1OC2=CC=C(C=C2)O
Synonyms

3-Monoiodothyronine
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Guo M, et al. A serum thyroid hormone metabolite test for molecular diagnostic evaluation of thyroid nodules. Cell Research. 2026 Oct 1:1-4.

[2]. Chen H, et al. Developmental toxicity of short-chain chlorinated paraffins on early-stage chicken embryos in a shell-less (ex-ovo) incubation system. Ecotoxicology and environmental safety. 2024 May;276:116304.

[3]. Richards KH, et al. A validated LC-MS/MS method for cellular thyroid hormone metabolism: Uptake and turnover of mono-iodinated thyroid hormone metabolites by PCCL3 thyrocytes. PloS one. 2017;12(8):e0183482.

[4]. Tanoue R, et al. Determination of free thyroid hormones in animal serum/plasma using ultrafiltration in combination with ultra-fast liquid chromatography-tandem mass spectrometry. Journal of chromatography. A. 2018 Mar 02;1539:30-40.

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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