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Cat. No.: HY-W142497

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3-Methyl-2(5H)-furanone

Name: 3-Methyl-2(5H)-furanone
Brand: MedChemExpress
SKU: HY-W142497
Price: 194.00 USD
Availability: InStock
Rating: 5 (1 reviews)

3-Methyl-2 (5H)-furanone is a volatile natural product and a furanone containing a furan ring discovered from the dichloromethane extract of Celtis durandii. 3-Methyl-2 (5H)-furanone inhibits biofilm formation of Klebsiella pneumoniae and reverses Xanthone (HY-N0126)- or Gentamicin (HY-A0276A)-induced biofilm. 3-Methyl-2 (5H)-furanone can be used in research on Klebsiella pneumoniae infection.

For research use only. We do not sell to patients.

Purity : 97.34%
CAS No.: 22122-36-7
Formula: C₅H₆O₂
Molecular Weight:98.10

Storage:

Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

3-Methyl-2(5H)-furanone Chemical Structure

CAS No.: 22122-36-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
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Biological Activity

Description

In Vitro

Bacterial Infection

3-Methyl-2(5H)-furanone (0.001 μM; 30 h) inhibits biofilm formation in Klebsiella pneumoniae by 56.4% and reverses Xanthone (HY-N0126)- or Gentamicin (HY-A0276A)-induced biofilm, producing net reductions up to 64.3% with α-mangostin at 0 h^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 22122-36-7
Appearance Liquid (Density: 1.13 g/cm³)
Molecular Weight 98.10
Formula C₅H₆O₂
Color Light yellow to yellow
SMILES

O=C1OCC=C1C
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (279 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liardon R, et al. Volatile Components of Fermented Soya Hydrolysate. I. Identification of Some Lactones. Z Lebensm Unters Forsch. 1978;167:180-185.

[2]. Ezenyi IC, et al. Marmesin isolated from Celtis durandii Engl. root bioactive fraction inhibits β-hematin formation and contributes to antiplasmodial activity. Journal of ethnopharmacology. 2023 Dec 05;317:116804.

[3]. Carmona-Orozco ML, et al. Reversing the biofilm-inducing effect of two xanthones from Garcinia mangostana by 3-methyl-2(5H)-furanone and N-butyryl-D-L homoserine lactone. Phytomedicine. 2023 Nov;120:155069.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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