3'-NH2-ddT
Based on 1 Customer Validation
3'-NH2-ddT (3′-Amino-2′,3′-dideoxythymidine) is a monomeric raw material that can be used for nucleic acid synthesis.
For research use only. We do not sell to patients.
- Purity : 96.88%
- CAS No.: 52450-18-7
- Formula: C10H15N3O4
- Molecular Weight:241.24
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| D-38 | ED50 |
100 μM
Compound: 1
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In vitro cytotoxicity against human D-38 cells.
In vitro cytotoxicity against human D-38 cells.
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[PMID: 6854592] |
| Huh-7 | CC50 |
>100 μg/mL
Compound: 8
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Cytotoxicity against human HuH7 cells by XTT assay
Cytotoxicity against human HuH7 cells by XTT assay
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[PMID: 22178557] |
| L1210 | ED50 |
0.8 μM
Compound: 3'-AdThd
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Compound was tested in vitro for cytotoxicity against L1210 leukemia cells in tumor bearing mice.
Compound was tested in vitro for cytotoxicity against L1210 leukemia cells in tumor bearing mice.
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[PMID: 2939245] |
| L929 | ED50 |
3 μM
Compound: 1
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in vitro cytotoxicity against mouse L cells.
in vitro cytotoxicity against mouse L cells.
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[PMID: 6854592] |
Chemical Information
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CAS No. 52450-18-7
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Appearance Solid
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Molecular Weight 241.24
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Formula C10H15N3O4
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Color White to off-white
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SMILES
O=C(NC(C(C)=C1)=O)N1[C@@H]2O[C@H](CO)[C@@H](N)C2
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Synonyms
3′-Amino-2′,3′-dideoxythymidine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (414.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (245 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1452 mL | 20.7262 mL | 41.4525 mL | 103.6312 mL |
| 5 mM | 0.8290 mL | 4.1452 mL | 8.2905 mL | 20.7262 mL | |
| 10 mM | 0.4145 mL | 2.0726 mL | 4.1452 mL | 10.3631 mL | |
| 15 mM | 0.2763 mL | 1.3817 mL | 2.7635 mL | 6.9087 mL | |
| 20 mM | 0.2073 mL | 1.0363 mL | 2.0726 mL | 5.1816 mL | |
| 25 mM | 0.1658 mL | 0.8290 mL | 1.6581 mL | 4.1452 mL | |
| 30 mM | 0.1382 mL | 0.6909 mL | 1.3817 mL | 3.4544 mL | |
| 40 mM | 0.1036 mL | 0.5182 mL | 1.0363 mL | 2.5908 mL | |
| 50 mM | 0.0829 mL | 0.4145 mL | 0.8290 mL | 2.0726 mL | |
| 60 mM | 0.0691 mL | 0.3454 mL | 0.6909 mL | 1.7272 mL | |
| 80 mM | 0.0518 mL | 0.2591 mL | 0.5182 mL | 1.2954 mL | |
| 100 mM | 0.0415 mL | 0.2073 mL | 0.4145 mL | 1.0363 mL |
3'-NH2-ddT Related Classifications
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