5'-Cholesteryl phosphoramidite
5'-Cholesteryl phosphoramidite is an antisense oligonucleotide conjugate targeting the p75 nerve growth factor receptor. 5'-Cholesteryl phosphoramidite downregulates the mRNA and protein levels of p75. 5'-Cholesteryl phosphoramidite enhances the cellular uptake efficiency of conjugated phosphorothioate oligonucleotides in differentiated PC12 cells.
For research use only. We do not sell to patients.
- CAS No.: 143723-64-2
- Formula: C43H76N3O4P
- Molecular Weight:730.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 143723-64-2
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Molecular Weight 730.06
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Formula C43H76N3O4P
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SMILES
C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCCCCCOP(OCCC#N)N(C(C)C)C(C)C)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)