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Cat. No.: HY-132141

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5-PA-dUTP

Name: 5-PA-dUTP
Brand: MedChemExpress
SKU: HY-132141
Price: 495.00 USD
Availability: PreOrder

(Synonyms: 5-Propargylamino-dUTP)

5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery. 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

CAS No.: 179101-49-6
Formula: C₁₂H₁₈N₃O₁₄P₃
Molecular Weight:521.20

Storage:

Solution, -20°C, 2 years

5-PA-dUTP Chemical Structure

CAS No.: 179101-49-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery^[1]. 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 179101-49-6
Appearance Liquid
Molecular Weight 521.20
Formula C₁₂H₁₈N₃O₁₄P₃
Color Colorless to light yellow
SMILES

O=C1N([C@H]2C[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O2)C=C(C(N1)=O)C#CCN
Synonyms

5-Propargylamino-dUTP
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (191.86 mM; Need ultrasonic)

View the Complete Stock Solution Preparation Table

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kyoung-Ran Kim, et al.Shaping Rolling Circle Amplification Products into DNA Nanoparticles by Incorporation of Modified Nucleotides and Their Application to In Vitro and In Vivo Delivery of a Photosensitizer. Molecules. 2018 Jul 23;23(7):1833. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
H₂O	1 mM	1.9186 mL	9.5932 mL	19.1865 mL	47.9662 mL
	5 mM	0.3837 mL	1.9186 mL	3.8373 mL	9.5932 mL
	10 mM	0.1919 mL	0.9593 mL	1.9186 mL	4.7966 mL
	15 mM	0.1279 mL	0.6395 mL	1.2791 mL	3.1977 mL
	20 mM	0.0959 mL	0.4797 mL	0.9593 mL	2.3983 mL
	25 mM	0.0767 mL	0.3837 mL	0.7675 mL	1.9186 mL
	30 mM	0.0640 mL	0.3198 mL	0.6395 mL	1.5989 mL
	40 mM	0.0480 mL	0.2398 mL	0.4797 mL	1.1992 mL
	50 mM	0.0384 mL	0.1919 mL	0.3837 mL	0.9593 mL
	60 mM	0.0320 mL	0.1599 mL	0.3198 mL	0.7994 mL
	80 mM	0.0240 mL	0.1199 mL	0.2398 mL	0.5996 mL
	100 mM	0.0192 mL	0.0959 mL	0.1919 mL	0.4797 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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100 mg

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