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Cat. No.: HY-158845

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8Br-HA

8Br-HA is a potent FHIT inhibitor with an IC₅₀ of 0.12 μM. 8 BR-HA can induceApoptosis. 8Br-HA has antitumor activity.

For research use only. We do not sell to patients.

CAS No.: 2937864-01-0
Formula: C₁₅H₁₄BrNO₅
Molecular Weight:368.18

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

8Br-HA Chemical Structure

CAS No.: 2937864-01-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

8Br-HA is a potent FHIT inhibitor with an IC₅₀ of 0.12 μM. 8 BR-HA can induceApoptosis. 8Br-HA has antitumor activity^[1].

IC₅₀ & Target

IC50：0.12 μM (FHIT) ^[1].

Chemical Information

CAS No. 2937864-01-0
Appearance Solid
Molecular Weight 368.18
Formula C₁₅H₁₄BrNO₅
Color White to off-white
SMILES

O=C1OC2=C(C3=C1CCCC3)C=CC(OCC(NO)=O)=C2Br
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hartman G, et al. The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening. Bioorg Med Chem Lett. 2024 Feb 28;102:129675. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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