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D-(+)-Trehalose dihydrate

(Synonyms: D-Trehalose dihydrate; α,α-Trehalose dihydrate)
11 Cited Publications
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Based on 11 publication(s) in Google Scholar

D-(+)-Trehalose dihydrate, isolated from Saccharomyces cerevisiae, can be used as a food ingredient and pharmaceutical excipient.

For research use only. We do not sell to patients.

  • Purity : 98.0%
  • CAS No.: 6138-23-4
  • Formula: C12H26O13
  • Molecular Weight:378.33
  • Storage:

    4°C, stored under nitrogen

    * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

  • D-(+)-Trehalose dihydrate Chemical Structure
    D-(+)-Trehalose dihydrate Chemical Structure
  • Experimental Validation Results for D-(+)-Trehalose dihydrate
  • Experimental Validation Results for D-(+)-Trehalose dihydrate
  • Experimental Validation Results for D-(+)-Trehalose dihydrate
  • Experimental Validation Results for D-(+)-Trehalose dihydrate
  • Experimental Validation Results for D-(+)-Trehalose dihydrate
  • Experimental Validation Results for D-(+)-Trehalose dihydrate
CAS No.: 6138-23-4
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  • D-(+)-Trehalose dihydrate Chemical Structure
    D-(+)-Trehalose dihydrate Chemical Structure
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    D-(+)-Trehalose dihydrate purchased from MedChemExpress. Usage Cited in: Res Sq. 2025 Jul 13.

    Customer Validation
     D-(+)-Trehalose (trehalose) (50 mM; 24 h). Secondary screen cell-based assay for p62 expression. Dot plot representation of the effects of the 17 compounds on p62 expression after 24 hours of treatment and cell viability. Quantification of total p62 puncta area following treatment relative to the control DMSO 0.1%, using HCS Studio software. Each bar represents the mean ± SD (n=3).

  • 1/16

    D-(+)-Trehalose dihydrate purchased from MedChemExpress. Usage Cited in: Res Sq. 2025 Jul 13.

    Customer Validation
     D-(+)-Trehalose (trehalose) (50 mM; 24 h). Cell-based screen for drug efficacy on membrane repair phenotype. Measurement of cell mortality after hypo-osmotic shock on DYSFS1173X immortalized myoblasts pretreated for 24 hours with the 17 compounds. Each point represents the mean ± SD (n=4) of a representative experiment from three independent experiments.

  • 1/16

    D-(+)-Trehalose dihydrate purchased from MedChemExpress. Usage Cited in: Ren Fail. 2024 Dec;46(1):2338933. [Abstract]

    Customer Validation
     D-(+)-Trehalose (Tre) (50 mM; 2 h). The expression of cytoplasmic TFEB and nuclear TFEB was analyzed by western blotting.

  • 1/16

    D-(+)-Trehalose dihydrate purchased from MedChemExpress. Usage Cited in: Ren Fail. 2024 Dec;46(1):2338933. [Abstract]

    Customer Validation
     D-(+)-Trehalose (Tre) (50 mM; 2 h). Autophagic vacuoles in HK-2 cells were observed by the transmission electron microscope, and yellow arrows represented autophagic vacuoles (×4,000, or ×30,000).

  • 1/16

    D-(+)-Trehalose dihydrate purchased from MedChemExpress. Usage Cited in: Ren Fail. 2024 Dec;46(1):2338933. [Abstract]

    Customer Validation
     D-(+)-Trehalose (Tre) (50 mM; 2 h). The mRNA levels of fibronectin, collagen I, α-SMA and E-cadherin were assessed by RT-qPCR.

  • 1/16

    D-(+)-Trehalose dihydrate purchased from MedChemExpress. Usage Cited in: Ren Fail. 2024 Dec;46(1):2338933. [Abstract]

    Customer Validation
     D-(+)-Trehalose (Tre) (50 mM; 2 h). E-cadherin and α-SMA was detected by immunoinfluorence staining (Bar = 25 μm).

  • D-(+)-Trehalose dihydrate