Caesalpiniaceae Extract

Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism.

3-(4-Nitrophenyl)-1H-pyrazol-5(4H)-one is a natural product found in Caesalpinia sappan. Caesalpinia sappan contains various phytochemicals and is considered a plant with significant medicinal value.

Cassiaside B2 is a protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A) inhibitor. Cassiaside B2 possesses antiallergic and is a 5-HT2C receptor agonist...

2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia.

Rubrofusarin 6-O-β-D-glucopyranoside, the glycoside of Rubrofusarin, is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with the IC₅₀ of 87.36 μM. Rubrofusarin 6-O-β-D-glucopyranoside can be used for the research of comorbid diabetes and depression.

Toralactone (Standard) is the analytical standard of Toralactone (HY-N7617). This product is intended for research and analytical applications. Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism.

Caesalpinia sappan polysaccharide is a polysaccharide derived from Caesalpinia sappan.

Cassiaside B, a naphthopyrone, has potent antimicrobial activity.

Obtusinaphthalenside B is a novel naphthyl glycoside compound that can be isolated from Cassia obtusifolia seeds. Cassia obtusifolia has physiological functions related to neuroprotection, anti-inflammation, and hepatoprotection.

Obtusichromoneside B is a novel naphthyl glycoside compound that can be isolated from Cassia obtusifolia seeds. Cassia obtusifolia possesses various physiological functions, including neuroprotection, anti-inflammatory effects, and hepatoprotection.

(3R)-Cassialactone 9-O-β-gentiobioside is a novel naphtholactone glycoside compound that can be isolated from the seeds of Cassia obtusifolia. The natural source plant of (3R)-Cassialactone 9-O-β-gentiobioside belongs to the Cassia genus and has traditional tonic and preventative effects.

Obtusichromoneside A is a chromone C-glycoside glycoside found in the Cassia obtusifolia seeds.

Obtusichromoneside C is a chromone C-glycoside found in the seeds of Cassia obtusifolia. Obtusichromoneside C regulates substance transport by inhibiting substrate uptake of specific transporters (e.g., OAT3, OATP1B3). Obtusichromoneside C is promising for research of drug transport.

Cassiaside C2 is a naphthopyrone with a strong antiallergic activity. Cassiaside C2 inhibits the histamine release from rat peritoneal exudate mast cells induced by antigen-antibody reaction.

2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy-3-methylanthraquinone can be found in the seeds of Cassia obtusifolia.

Torososide B is an antiallergic compound that inhibits calcium ionophore A-induced leukotriene release from rat peritoneal mast cells.

OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-2 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-2 can be used to study mercury-induced kidney damage.

OAT1/3-IN-1 (compound 7) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-1 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-1 can be used to study mercury-induced kidney damage.

6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (compound 1) is an anthraquinone α-glucosidase inhibitor (IC₅₀:185 μM), which can be isolated from Cassia seeds.

Xanrhorin is an anthraquinone agent.