Podocarpaceae Extract

Myricitrin, a naturally occurring flavonoid, is an orally active nitric oxide (NO) and PKC inhibitor. Myricitrin has central nervous system activity, including anxiolytic-like action. Myricitrin possesses antioxidant, anti-inflammatory, antifibrotic and anti-malarial effects.

Ponasterone A (25-Deoxyecdysterone), an ecdysteroid, has strong affinity for the ecdysone receptor. Ponasterone A is a potent regulator of gene expression in cells and transgenic animals, enabling reporter genes to be turned on and off rapidly.

Myricetin (Standard) is the analytical standard of Myricetin. This product is intended for research and analytical applications. Myricetin is a common plant-derived flavonoid with a wide range of activities including strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities.

Alphitolic acid (Aophitolic acid), an anti-inflammatory triterpenoid compound, is a selective HMGCS2 inhibitor (IC50 17.17 μM, Kd 5.6 μM). Alphitolic acid inhibits ORAI1/STIM1-mediated CRAC currents, store-operated calcium entry, the Akt-mTOR-NF-κB signaling pathway, p70S6K/S6/IκBα phosphorylation, NF-κB/Bcl-2 expression, and NO/TNF-α production, while upregulating p53 and downregulating MDM2. Alphitolic acid induces apoptosis (apoptosis) and autophagy (autophagy) through Beclin 1, Atg7, LC3B-II, and autophagosomes, inhibits oral squamous cell carcinoma proliferation/viability, and exhibits antibacterial/antimalarial/antioxidant activities. Alphitolic acid can be used in research on inflammatory diseases, allergic diseases, Tamoxifen (HY-13757A)-resistant breast cancer, oral squamous cell carcinoma, and inflammation.

Myricanone is a compound isolated from the bark of Myrica rubra.

Myricitrin (Standard) is the analytical standard of Myricitrin. This product is intended for research and analytical applications. Myricitrin, a naturally occurring flavonoid, is an orally active nitric oxide (NO) and PKC inhibitor. Myricitrin has central nervous system activity, including anxiolytic-like action. Myricitrin possesses antioxidant, anti-inflammatory, antifibrotic and anti-malarial effects.

Podecdysone B is a phytoecdysone isolated from Cyanotis arachnoidea.

Nagilactone B is a liver X receptor (LXR) agonist.

3β,5α-Dihydroxystigmastan-6-one is a natural steroid.

Podocarpusflavone B is a bisflavone that can be isolated from Padocarpus macraphylla.

Nagilactone C is a diterpene dilactone compound isolated from Podocarpus neriifolius. Nagilactone C has potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines.

Myricananin A is a colorless needle that has inhibitory effect on iNOS.

Myriceric acid C, a saturated fatty acid, is a natural product that can be isolated from Myrica cerifera.

2,3-Dihydroisoginkgetin, a biflavonoid, is a inhibitor of Tyrosinase, with 36.84% inhibition at 0.1 mM. 2,3-Dihydroisoginkgetin shows less toxicity in HEMn (human epidermal melanocytes) cells, with an IC₅₀ of 86.16 μM.

Rospiglioside aglycon (4beta-Carboxynortotarol) is a Miscellaneous product that can be isolated from the herbs of Conyza stricta.

9,13-Epidioxy-8(14)-abieten-18-oic acid is a Diterpenoids product that can be isolated from the heartwoods of Podocarpus macrophyllus.

Totaradiol ((+)-Totaradiol; 3β-Hydroxytotarol) is a diterpene can be isolated from Thuja plicata (Cupressaceae).