CD3 Agonist
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IBI38D9-L
0 ImagesCat. No.: HY-P992547IBI38D9-L is a human IgG1-type CD79b/CD3 bispecific T-cell engager. IBI38D9-L binds to human CD79b and CD3 with Kd values of 1.45 nM and 119 nM, respectively. IBI38D9-L mediates tumor cell recognition and T-cell engagement, activating T cells and inducing their proliferation and release of cytotoxic molecules. IBI38D9-L exerts T cell-mediated cytotoxicity in a tumor cell-dependent manner, thereby selectively depleting antigen-positive malignant B cells. IBI38D9-L can be used for research on B-cell non-Hodgkin lymphoma.
