PNPLA3 Inhibitor

PNPLA3 Human Pre-designed siRNA Set A contains three designed siRNAs for PNPLA3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Edutirsen, an antisense oligonucleotide, is a 1-acylglycerol-3-phosphate O-acyltransferase (PNPLA3) synthesis reducer.

Pivicasiran sodium, a siRNA, is a adiponutrin synthesis reducer.

NUV-244 is a molecular glue degrader of PNPLA3 ^I148M. NUV-244 induces degradation via the ubiquitin-proteasome system involving the E3 ligase BFAR. NUV-244 promotes 26S proteasome-dependent degradation of PNPLA3 ^I148M. NUV-244 restores lipid droplet morphology and cellular fitness in hepatocytes expressing PNPLA3 ^I148M. NUV-244 can be used in the research of metabolic dysfunction-associated fatty liver disease.

Pivicasiran sodium scrambled negative control is the sequence scrambled negative control of Pivicasiran sodium.

Edutirsen sodium, an antisense oligonucleotide, is a 1-acylglycerol-3-phosphate O-acyltransferase (PNPLA3) synthesis reducer.

Pivicasiran, a siRNA, is a adiponutrin synthesis reducer.