AChE/BChE-IN-39
AChE/BChE-IN-39 (compound 6) is a potent dual AChE/BChE inhibitor with IC50 values of 751.62 pM and 73.51 pM, respectively. AChE/BChE-IN-39 maintains acetylcholine levels through mixed-type inhibition at the catalytic site and peripheral choline esterase site. AChE/BChE-IN-39 can be used for research on Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C20H12ClFN2OS
- Molecular Weight:382.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
EeAChE 751.62 pM (IC50) |
EeAChE 371.04 pM (Ki) |
equine serum BChE 73.51 pM (IC50) |
equine serum BChE 43.52 pM (Ki) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 382.84
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Formula C20H12ClFN2OS
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SMILES
O=C(C1=CC=C(Cl)C=C1)/C=C/C2=C(C3=CC=C(F)C=C3)N=C4SC=CN42
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)