AChE/BChE-IN-43
AChE/BChE-IN-43 is a dual AChE/BChE inhibitor (Electrophorus electricus AChE (Ki = 29.05 nM) and equine serum BChE (Ki = 28.68 nM)). AChE/BChE-IN-43 can be used in the research of Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C31H27F3N4O4
- Molecular Weight:576.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
electric eel AChE 29.05 nM (Ki) |
equine serum BChE 28.68 nM (Ki) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| SH-SY5Y | IC50 |
41.53 μM
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Cytotoxicity against human neuroblastoma SH-SY5Y cells assessed as reduction in cell viability incubated for 24 hrs by crystal violet staining method.
Cytotoxicity against human neuroblastoma SH-SY5Y cells assessed as reduction in cell viability incubated for 24 hrs by crystal violet staining method.
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42585890 |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 576.57
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Formula C31H27F3N4O4
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SMILES
COC1=CC(/C=N/NC(C2=CC=C(C=C2)OC3=NC=CC=C3C(F)(F)F)=O)=CC(CN4CC5=C(C=CC=C5)CC4)=C1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE/BChE-IN-43 Related Classifications
HY-189408 Related Classifications
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