Adenosine-2'-monophosphate (Standard)
Adenosine-2'-monophosphate (Standard) (2'-AMP (Standard)) is the analytical standard of Adenosine-2'-monophosphate (HY-124151). This product is intended for research and analytical applications. Adenosine-2'-monophosphate (2'-AMP) is converted by extracellular 2’,3'-CAMP. Adenosine-2'-monophosphate is further metabolized to extracellular adenosine (a mechanism called the extracellular 2’,3’-cAMP-adenosine pathway). Adenosine-2'-monophosphate inhibits LPS-induced TNF-α and CXCL10 production via A2A receptor activation.
For research use only. We do not sell to patients.
- CAS No.: 130-49-4
- Formula: C10H14N5O7P
- Molecular Weight:347.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 130-49-4
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Molecular Weight 347.22
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Formula C10H14N5O7P
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SMILES
O=[P](O)(O)O[C@H]([C@@H]1O)[C@@](N2C3=NC=NC(N)=C3N=C2)([H])O[C@@H]1CO
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Synonyms
2'-AMP (Standard); Adenosine 2'-phosphate (Standard); AMP 2'-phosphate (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Jackson EK, Gillespie DG, Dubey RK. 2'-AMP and 3'-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. J Pharmacol Exp Ther. 2011;337(2):444‐450. [Content Brief]
[2]. Newell EA, Exo JL, Verrier JD, et al. 2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors. Brain Res. 2015;1594:27‐35. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)