Adosupine
Adosupine is a tricyclic compound that affects detrusor hyperreflexia via central nervous system sites. Adosupine can be used in studies related to detrusor hyperreflexia and urinary incontinence.
For research use only. We do not sell to patients.
- CAS No.: 88124-26-9
- Formula: C17H14N2O3
- Molecular Weight:294.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Adosupine maintains stability for up to 2 years when stored at 40-50°C or room temperature, either protected from light or exposed to light. Moreover, it exhibits extremely high stability when stored at room temperature for up to 60 months[2].
Adosupine remains stable for 320 days in acidic aqueous suspensions as well as reductive/oxidative aqueous solutions, whereas it degrades via lactam ring hydrolysis in neutral and basic aqueous suspensions over the same period[2].
Adosupine exists in only one crystalline form, and its amorphous form can be obtained by evaporating its dichloromethane solution at room temperature[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Chemical Information
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CAS No. 88124-26-9
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Molecular Weight 294.30
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Formula C17H14N2O3
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SMILES
O=C1C2=C(N(C)C(C3=C1C(NC(C)=O)=CC=C3)=O)C=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. D'Aranno V, et al. Determination of the tricyclic compound adosupine and its three metabolites in plasma and brain of rat using high-performance liquid chromatography. Journal of chromatography. 1992 Feb 14;574(2):319-25. [Content Brief]
[2]. Perico A, et al. Synthesis, characterization, and analytical studies of adosupine, a potential new drug for urinary incontinence. Journal of pharmaceutical sciences. 1994 Feb;83(2):137-42. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Adosupine Related Classifications
HY-184039 Related Classifications
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