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Cat. No.: HY-N20724

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Ageconyflavone C

Ageconyflavone C is a natural pentamethoxyflavonoid found in the aerial parts of Ageratum conyzoides L. Ageconyflavone C inhibits Trypanosoma brucei rhodesiense, Leishmania donovani, and Chloroquine (HY-17589A)- and Pyrimethamine (HY-18062)-resistant Plasmodium falciparum K1, with IC₅₀ values of 7.8, 9.2, and 9.25 μM, respectively. Ageconyflavone C can be used in studies related to anti-protozoal and parasitic infection research.

For research use only. We do not sell to patients.

CAS No.: 93124-90-4
Formula: C₂₀H₂₀O₈
Molecular Weight:388.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ageconyflavone C Chemical Structure

CAS No.: 93124-90-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

All Parasite Isoforms :

In Vitro

Parasitic Infection

Ageconyflavone C (compound 5) (>30 μg/mL; >90 μg/mL) exhibits moderate in vitro antiprotozoal activity against Trypanosoma brucei rhodesiense (IC₅₀ = 7.8 μM), Leishmania donovani (IC₅₀ = 9.2 μM), and Plasmodium falciparum (IC₅₀ = 9.25 μM), with no activity against Trypanosoma cruzi and no cytotoxicity against L6 rat skeletal myoblasts at the highest tested concentrations^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Infectious Diseases

Chemical Information

CAS No. 93124-90-4
Molecular Weight 388.37
Formula C₂₀H₂₀O₈
SMILES

O=C1C=C(C2=CC(OC)=C(O)C(OC)=C2)OC3=C1C(OC)=C(OC)C(OC)=C3
Structure Classification
- Flavonoids
- Flavonols
- Phenols
- Monophenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Nour AM, et al. The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L. Journal of ethnopharmacology. 2010 May 04;129(1):127-30. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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