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Cat. No.: HY-P3162

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(Ala13)-Apelin-13

Name: (Ala13)-Apelin-13
Brand: MedChemExpress
SKU: HY-P3162
Availability: PreOrder

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway.

For research use only. We do not sell to patients.

CAS No.: 568565-11-7
Formula: C₆₃H₁₀₇N₂₃O₁₆S
Molecular Weight:1474.73

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(Ala13)-Apelin-13 Chemical Structure

CAS No.: 568565-11-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Publications (1)
Purity & Documentation
References
Calculators
Help & FAQs
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Bioz

Biological Activity

Description

(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway^[1].

In Vivo

(Ala13)-Apelin-13 (1-300 pmol/60 nl; microinjected into the DVC) decreases gastric tone and motility in a dose-dependent manner in rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

250-300 g, Sprague-Dawley rats^[1]
Dosage:

1-300 pmol/60 nl
Administration:

Microinjected into the DVC (dorsal vagal complex (DVC)
Result:

Decreased gastric tone and motility in a dose-dependent manner with D50 ≈ 27 pmol for both antrum and corpus.

Chemical Information

CAS No. 568565-11-7
Molecular Weight 1474.73
Formula C₆₃H₁₀₇N₂₃O₁₆S
Sequence

Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala
Sequence Shortening

QRPRLSHKGPMPA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Bratisl Lek Listy

2026 Aug 22.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bülbül M, et al. Apelin-13 inhibits gastric motility through vagal cholinergic pathway in rats. Am J Physiol Gastrointest Liver Physiol. 2018 Feb 1;314(2):G201-G210. [Content Brief]

[2]. O'Harte FPM,et al. Acylated apelin-13 amide analogues exhibit enzyme resistance and prolonged insulin releasing, glucose lowering and anorexic properties. Biochem Pharmacol. 2017 Dec 15;146:165-173. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

(Ala13)-Apelin-13

1 Cited Publications

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Biological Activity
- Description
- In Vivo
Chemical Information
Publications (1)
Purity & Documentation
References

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(Ala13)-Apelin-13

Publications Citing Use of MedChemExpress (MCE) (Ala13)-Apelin-13