Copy Link Print Information

Alemtuzumab

(Synonyms: Campath-IH)
Customer Review

Based on 1 Customer Validation

Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52. Alemtuzumab does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. Alemtuzumab is capable of complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induction of apoptosis. Alemtuzumab has the potential for B-cell chronic lymphocytic leukaemia research.

For research use only. We do not sell to patients.

  • Purity : 99.719%
  • CAS No.: 216503-57-0
  • Molecular Weight:146.06 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Alemtuzumab
  • Experimental Validation Results for Alemtuzumab
  • Experimental Validation Results for Alemtuzumab
  • Alemtuzumab Chemical Structure
    Alemtuzumab Chemical Structure
CAS No.: 216503-57-0
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Alemtuzumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Protocols
  • Purity & Documentation
  • References
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Keywords

MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow cytometry analysis of PBMC cells labelling CD52 with Alemtuzumab at 20 nM (Red). Goat anti human IgG Fc (Alexa Fluor488) was used as the secondary antibody at 1/1000 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).

  • 1/16

    Immobilized CD52 Protein, Human (His, HY-P72123) can bind Alemtuzumab. The EC50 for this effect is 1.1 ng/mL.

  • Alemtuzumab Chemical Structure
    1/16
  • Alemtuzumab
  • Flow cytometry analysis of PBMC cells labelling CD52 with Alemtuzumab at 20 nM (Red). Goat anti human IgG Fc (Alexa Fluor488) was used as the secondary antibody at 1/1000 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).
  • Immobilized CD52 Protein, Human (His, HY-P72123) can bind Alemtuzumab. The EC50 for this effect is 1.1 ng/mL.