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Cat. No.: HY-184730

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Antifungal agent 171

Antifungal agent 171 is a mitochondrial complex III inhibitor with a Botrytis cinerea IC₅₀ of 6.48 mg/L. Antifungal agent 171 interferes with respiratory metabolism by binding to mitochondrial complex III and exhibits broad-spectrum inhibitory activity against Valsa mali, Botrytis cinerea, and Physalospora piricola. Antifungal agent 171 can be used for the research of valsa mali infection, botrytis cinerea infection, physalospora piricola infection.

For research use only. We do not sell to patients.

Formula: C₁₇H₁₉ClN₂O₃
Molecular Weight:334.80

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antifungal agent 171 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Fungal Infection

Antifungal agent 171 (Compound D4) potently inhibits mycelia growth of Valsa mali, Botrytis cinerea, and Physalospora piricola with EC₅₀ values of 2.17 mg/L, 0.479 mg/L, and 4.84 mg/L, respectively^[1].
Antifungal agent 171 (5 mg/L) causes severe morphological damage and clumping of Botrytis cinerea hyphae^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Fungal Infection

Antifungal agent 171 (Compound D4) (100 ng/L; evenly sprayed) exhibits protective activity against Valsa mali in apple plants^[1].
Antifungal agent 171 (50-100 ng/L; evenly sprayed) exhibits significant activity against Botrytis cinerea in tomato fruits^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Infectious Diseases

Chemical Information

Molecular Weight 334.80
Formula C₁₇H₁₉ClN₂O₃
SMILES

O=C(OC)/C(CC1=CN(C/C=C(C)\C)C2=C1C=CC(Cl)=C2)=N/O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Gong XS, et al. Optimization of Luteoride A Derivatives as Potential Broad-Spectrum Fungicide Agents for Plant Protection. Journal of agricultural and food chemistry. 2026 Jul 22;74(28):22279-22289. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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