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Cat. No.: HY-W035445

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Antiparasitic agent-42

Antiparasitic agent-42 is an orally active p-aminophenoxyalkane derivative with anti-Schistosoma mansoni activity. Antiparasitic agent-42 exerts retinal toxicity in cats. Antiparasitic agent-42 can be used in the research of schistosomiasis.

For research use only. We do not sell to patients.

CAS No.: 102010-61-7
Formula: C₁₉H₂₃NO₃
Molecular Weight:313.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antiparasitic agent-42 Chemical Structure

CAS No.: 102010-61-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
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Biological Activity

Description

All Parasite Isoforms :

In Vivo

Parasitic InfectionOthers

Parasitic Infection

Antiparasitic agent-42 (compound 2576) (administered orally daily for 4 consecutive days) exhibits anti-schistosomal activity in mice infected with Schistosoma mansoni. Its single oral LD₅₀ is 1.5 g/kg, daily LD₅₀ is 0.56 g/kg, and daily CD₅₀ is 0.33 g/kg^[1].

Others

Antiparasitic agent-42 (single oral dose ≤0.4 g/kg) induces ocular retinal toxicity in healthy adult male and female cats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 102010-61-7
Molecular Weight 313.40
Formula C₁₉H₂₃NO₃
SMILES

O=C(C1=CC=C(OCCCCCOC2=CC=C(N)C=C2)C=C1)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Collins RF, et al. The schistosomicidal and toxic effects of some αω-di(p-aminophenoxy)alkanes and related monoamines. British Journal of Pharmacology and Chemotherapy. 1958;13(3):238-243.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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