Apixaban impurity 45
Based on 1 Customer Validation
Apixaban impurity 45 (Apixaban Dehydro impurity) is an impurity of Apixaban.
For research use only. We do not sell to patients.
- Purity : 98.00%
- CAS No.: 1074549-89-5
- Formula: C25H23N5O4
- Molecular Weight:457.49
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
Chemical Information
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CAS No. 1074549-89-5
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Appearance Solid
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Molecular Weight 457.49
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Formula C25H23N5O4
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Color White to off-white
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SMILES
O=C(N)C1=NN(C2=CC=C(OC)C=C2)C=3C(=O)N(C=CC13)C4=CC=C(C=C4)N5C(=O)CCCC5
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Synonyms
Apixaban Dehydro impurity
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 30 mg/mL (65.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (247 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1858 mL | 10.9292 mL | 21.8584 mL | 54.6460 mL |
| 5 mM | 0.4372 mL | 2.1858 mL | 4.3717 mL | 10.9292 mL | |
| 10 mM | 0.2186 mL | 1.0929 mL | 2.1858 mL | 5.4646 mL | |
| 15 mM | 0.1457 mL | 0.7286 mL | 1.4572 mL | 3.6431 mL | |
| 20 mM | 0.1093 mL | 0.5465 mL | 1.0929 mL | 2.7323 mL | |
| 25 mM | 0.0874 mL | 0.4372 mL | 0.8743 mL | 2.1858 mL | |
| 30 mM | 0.0729 mL | 0.3643 mL | 0.7286 mL | 1.8215 mL | |
| 40 mM | 0.0546 mL | 0.2732 mL | 0.5465 mL | 1.3662 mL | |
| 50 mM | 0.0437 mL | 0.2186 mL | 0.4372 mL | 1.0929 mL | |
| 60 mM | 0.0364 mL | 0.1822 mL | 0.3643 mL | 0.9108 mL |