Arundic Acid (Standard)
Arundic Acid (Standard) (ONO-2506 (Standard)) is the analytical standard of Arundic Acid (HY-107661). This product is intended for research and analytical applications. Arundic Acid is an orally effective astrocyte function modulator and neuroprotective agent. Arundic Acid increases the expression and function of the astrocytic glutamate transporter EAAT1 by activating the ERK, Akt and NF-κB pathways. Arundic Acid attenuates retinal ganglion cell death in a normal-tension glaucoma model. Arundic Acid exerts neuroprotective effects in a mouse model of Parkinson's disease. Arundic Acid is a S100β protein synthesis inhibitor that prevents neurological deficits and brain tissue damage after intracerebral hemorrhage in rats. Arundic Acid downregulates neuroinflammation and astrocytic dysfunction after status epilepticus in immature rats. Arundic Acid is applicable to research related to Parkinson's disease, cerebral ischemia, glaucoma, intracerebral hemorrhage and epilepsy.
For research use only. We do not sell to patients.
- CAS No.: 185517-21-9
- Formula: C11H22O2
- Molecular Weight:186.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-107661
Arundic AcidAstrocyte Function Modulator/Neuroprotective Agent -
HY-P1240
MOG (35-55) mouse, ratCNS Myelin Component -
HY-P1242
NEP(1-40)NgR Antagonist -
HY-107660
SIRT2-IN-8SIRT2 Inhibitor -
HY-W096171
D-DopaGCPII Inhibitor -
HY-17587
4-Methylbenzylidene camphorEstrogen-Like Drug -
HY-107662
TCS PrP Inhibitor 13PrP C Inhibitor -
HY-17587R
4-Methylbenzylidene camphor (Standard)Estrogen-Like Drug -
![[SER140]-PLP(139-151)](https://file.medchemexpress.com/product_pic/hy-p1038.gif)
HY-P1038
[SER140]-PLP(139-151) -
HY-107662R
TCS PrP Inhibitor 13 (Standard)Reference Standard
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 185517-21-9
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Molecular Weight 186.29
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Formula C11H22O2
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SMILES
CCCCCC[C@H](C(O)=O)CCC
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Synonyms
ONO-2506 (Standard); (R)-2-Propyloctanoic acid (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Karki P, et al. Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-κB Pathways. Mol Neurobiol. 2018 Jun;55(6):5031-5046. [Content Brief]
[3]. Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTPneurotoxicity in mice. Brain Res. 2004 Dec 24;1030(1):66-73. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Arundic Acid (Standard) Related Classifications
HY-107661R Related Classifications
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