Belinostat glucuronide
Belinostat glucuronide (Belinostat G) is the major metabolite formed via UGT1A1-catalyzed O-glucuronidation of Belinostat (HY-10225), and exhibits no activity against cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 1486471-13-9
- Formula: C21H22N2O10S
- Molecular Weight:494.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human hepatocellular liver carcinoma HepG2 cells
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Concentration:0.1, 0.5, 1, 2, 5, 10 μM
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Incubation Time:72 h
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Result:Did not reduce the number of viable HepG2 cells in the Gentian Violet staining assay.
Showed no dose-dependent growth inhibition in the MTS assay, with an IC50 value unable to be converged.
Chemical Information
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CAS No. 1486471-13-9
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Molecular Weight 494.47
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Formula C21H22N2O10S
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SMILES
O=S(C1=CC=CC(/C=C/C(NO[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)C(O)=O)=O)=C1)(NC3=CC=CC=C3)=O
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Synonyms
Belinostat G
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)