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16Alpha-hydroxyprogesterone dehydratase

Definition:

EC Tree > 4 Lyases > 4.2 Carbon-oxygen lyases > 4.2.1 Hydro-lyases > 4.2.1.98 16alpha-hydroxyprogesterone dehydratase
16Alpha-hydroxyprogesterone dehydratase is a steroid dehydratase from Eubacterium sp. that dehydrates 16alpha-hydroxyprogesterone into 16,17-didehydroprogesterone and water; 16alpha-hydroxypregnenolone is also a substrate. Structurally it is a steroid dehydratase.

References:

[1]. Glass T.L., et al. Stimulation of 16-dehydroprogesterone and progesterone reductases of Eubacterium sp. strain 144 by hemin and hydrogen or pyruvate (1985), Appl. Environ. Microbiol. , 49, 1146-1153. [Content Brief]

[2]. Aoki H., et al. Isolation of 2-methylisocitrate dehydratase, a new enzyme serving in the methylcitric acid cycle for propionate metabolism, from Yallowia lipolytica (1995), Biosci. Biotechnol. Biochem., 59, 1825-1828.

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