4-Hydroxymandelate synthase
Definition:
EC Tree > 1 Oxidoreductases > 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) > 1.13.11 With incorporation of two atoms of oxygen > 1.13.11.46 4-hydroxymandelate synthase
4-Hydroxymandelate synthase is an Fe2+-requiring non-heme oxygenase found in bacteria and eukaryotes, involved in biosynthesis of the vancomycin-group glycopeptide antibiotics. It oxidizes 4-hydroxyphenylpyruvate with O2 by oxidative decarboxylation to (S)-4-hydroxymandelate plus CO2.
4-Hydroxymandelate synthase is an Fe2+-requiring non-heme oxygenase found in bacteria and eukaryotes, involved in biosynthesis of the vancomycin-group glycopeptide antibiotics. It oxidizes 4-hydroxyphenylpyruvate with O2 by oxidative decarboxylation to (S)-4-hydroxymandelate plus CO2.
References:
Biomedical Dictionary
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