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ABC-type polyamine transporter

Definition:

EC Tree > 7 Translocases > 7.6 Catalysing the translocation of other compounds > 7.6.2 Linked to the hydrolysis of a nucleoside triphosphate > 7.6.2.11 ABC-type polyamine transporter
ABC-type polyamine transporter imports putrescine and spermidine; Escherichia coli prefers spermidine. It is not phosphorylated. Structurally it is a PotABCD importer.

References:

[1]. Alliot J., et al. Polyamine transport system-targeted nanometric micelles assembled from epipodophyllotoxin-amphiphiles (2019), Chem. Commun. (Camb.) , 55, 14968-14971.

[2]. Benaouda F., et al. Ion-pairing with spermine targets theophylline to the lungs via the polyamine transport system (2018), Mol. Pharm. , 15, 861-870.

[3]. Ha J.H., et al. Evidence of link between quorum sensing and sugar metabolism in Escherichia coli revealed via cocrystal structures of LsrK and HPr (2018), Sci. Adv. , 4, eaar7063 .

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