Alpha,alpha-trehalose synthase
Definition:
EC Tree > 2 Transferases > 2.4 Glycosyltransferases > 2.4.1 Hexosyltransferases > 2.4.1.245 alpha,alpha-trehalose synthase
Alpha,alpha-trehalose synthase is a trehalose-biosynthetic enzyme that requires Mg2+. It reversibly transfers glucose from NDP-alpha-D-glucose onto D-glucose, releasing NDP and forming alpha,alpha-trehalose. In the reverse direction it is specific for alpha,alpha-trehalose and cannot use aryl glucosides, maltose, sucrose, lactose or cellobiose. The Rubrobacter xylanophilus and Pyrococcus horikoshii enzymes use ADP-, UDP- and GDP-alpha-D-glucose equally; Thermococcus litoralis prefers ADP- and Thermoproteus tenax prefers UDP-glucose. It occurs in Bacteria and Archaea.
Alpha,alpha-trehalose synthase is a trehalose-biosynthetic enzyme that requires Mg2+. It reversibly transfers glucose from NDP-alpha-D-glucose onto D-glucose, releasing NDP and forming alpha,alpha-trehalose. In the reverse direction it is specific for alpha,alpha-trehalose and cannot use aryl glucosides, maltose, sucrose, lactose or cellobiose. The Rubrobacter xylanophilus and Pyrococcus horikoshii enzymes use ADP-, UDP- and GDP-alpha-D-glucose equally; Thermococcus litoralis prefers ADP- and Thermoproteus tenax prefers UDP-glucose. It occurs in Bacteria and Archaea.
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