Alpha-gurjunene synthase

Definition:

EC Tree > 4 Lyases > 4.2 Carbon-oxygen lyases > 4.2.3 Acting on phosphates > 4.2.3.72 alpha-gurjunene synthase
Alpha-gurjunene synthase is a sesquiterpene cyclase. Initial cyclization probably gives enzyme-bound bicyclogermacrene which is not released; the Solidago canadensis enzyme also forms a small amount of (+)-gamma-gurjunene. It cyclizes (2E,6E)-farnesyl diphosphate into (-)-alpha-gurjunene and diphosphate. It appears in viruses and cellular organisms. Structurally it is a sesquiterpene cyclase.

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