Aristolochene synthase
Definition:
EC Tree > 4 Lyases > 4.2 Carbon-oxygen lyases > 4.2.3 Acting on phosphates > 4.2.3.9 aristolochene synthase
Aristolochene synthase is a sesquiterpene cyclase. Initial internal cyclization produces monocyclic germacrene A; further cyclization and methyl transfer convert it into aristolochene. In some species germacrene A remains enzyme-bound, but in Penicillium roqueforti it is a minor product (see EC 4.2.3.23). It cyclizes (2E,6E)-farnesyl diphosphate into aristolochene and diphosphate; aristolochene is the precursor of PR-toxin. Structurally it is a sesquiterpene cyclase.
Aristolochene synthase is a sesquiterpene cyclase. Initial internal cyclization produces monocyclic germacrene A; further cyclization and methyl transfer convert it into aristolochene. In some species germacrene A remains enzyme-bound, but in Penicillium roqueforti it is a minor product (see EC 4.2.3.23). It cyclizes (2E,6E)-farnesyl diphosphate into aristolochene and diphosphate; aristolochene is the precursor of PR-toxin. Structurally it is a sesquiterpene cyclase.
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
