Arylformamidase
Definition:
EC Tree > 3 Hydrolases > 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds > 3.5.1 In linear amides > 3.5.1.9 arylformamidase
Adenosylcobinamide hydrolase is an amidohydrolase found in archaea and bacteria, involved in the cobinamide salvage pathway in archaea. Archaea convert adenosylcobinamide (AdoCbi) into adenosylcobinamide phosphate (AdoCbi-P) in two steps: CbiZ cleaves off the aminopropanol moiety to give adenosylcobyric acid (AdoCby), then EC 6.3.1.10 (CbiB) converts AdoCby into AdoCbi-P. It hydrolyzes adenosylcobinamide into adenosylcobyric acid and (R)-1-aminopropan-2-ol. In archaea it salvages cobalamin precursors. It features an amidohydrolase fold.
Adenosylcobinamide hydrolase is an amidohydrolase found in archaea and bacteria, involved in the cobinamide salvage pathway in archaea. Archaea convert adenosylcobinamide (AdoCbi) into adenosylcobinamide phosphate (AdoCbi-P) in two steps: CbiZ cleaves off the aminopropanol moiety to give adenosylcobyric acid (AdoCby), then EC 6.3.1.10 (CbiB) converts AdoCby into AdoCbi-P. It hydrolyzes adenosylcobinamide into adenosylcobyric acid and (R)-1-aminopropan-2-ol. In archaea it salvages cobalamin precursors. It features an amidohydrolase fold.
References:
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