Astacin
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.24 Metalloendopeptidases > 3.4.24.21 astacin
Stromelysin 2 is an extracellular zinc metalloendopeptidase in peptidase family M10 (interstitial collagenase family). It digests gelatin types I, III, IV and V, fibronectin and proteoglycan; similar to stromelysin 1 but its action on collagen types III, IV and V is weak. In connective tissue it remodels the extracellular matrix. It features an M10 catalytic domain with hemopexin-like C-terminal domain.
Stromelysin 2 is an extracellular zinc metalloendopeptidase in peptidase family M10 (interstitial collagenase family). It digests gelatin types I, III, IV and V, fibronectin and proteoglycan; similar to stromelysin 1 but its action on collagen types III, IV and V is weak. In connective tissue it remodels the extracellular matrix. It features an M10 catalytic domain with hemopexin-like C-terminal domain.
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