Avermitilol synthase
Definition:
EC Tree > 4 Lyases > 4.2 Carbon-oxygen lyases > 4.2.3 Acting on phosphates > 4.2.3.96 avermitilol synthase
Avermitilol synthase is a Mg2+-dependent sesquiterpene cyclase from Streptomyces avermitilis; the recombinant enzyme gives avermitilol (85%) plus traces of germacrene A, germacrene B and viridiflorol; the (1S)-hydrogen of farnesyl diphosphate is retained. With water it converts (2E,6E)-farnesyl diphosphate into avermitilol and diphosphate. Structurally it is a bacterial sesquiterpene cyclase.
Avermitilol synthase is a Mg2+-dependent sesquiterpene cyclase from Streptomyces avermitilis; the recombinant enzyme gives avermitilol (85%) plus traces of germacrene A, germacrene B and viridiflorol; the (1S)-hydrogen of farnesyl diphosphate is retained. With water it converts (2E,6E)-farnesyl diphosphate into avermitilol and diphosphate. Structurally it is a bacterial sesquiterpene cyclase.
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
