Bothrolysin

Definition:

EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.24 Metalloendopeptidases > 3.4.24.50 bothrolysin
Ophiolysin is a 70-kDa zinc metalloendopeptidase from king cobra (Ophiophagus hannah) venom. It cleaves Asn3-/-Gln, Gln4-/-His, His10-/-Leu, Ala14-/-Leu and Tyr16-/-Leu in the insulin B chain. In venom it causes tissue damage. It features an M12-family zinc catalytic domain.

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