Catechol O-methyltransferase

Definition:

EC Tree > 2 Transferases > 2.1 Transferring one-carbon groups > 2.1.1 Methyltransferases > 2.1.1.6 catechol O-methyltransferase
Catechol O-methyltransferase (COMT) methylates catechols (and, in mammals, more rapidly the catecholamines adrenaline and noradrenaline) into guaiacols, degrading catecholamine neurotransmitters and catechol drugs; it is a major drug target for Parkinson's disease.

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