Cathepsin O
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.22 Cysteine endopeptidases > 3.4.22.42 cathepsin O
Cathepsin O is a lysosomal cysteine peptidase of family C1 (papain family). The recombinant human enzyme is catalytically active at pH 6.0 and inhibited by compound E-64. It is ubiquitously expressed in human tissues, with the human gene at locus 4q31-32. The recombinant human enzyme hydrolyzes synthetic endopeptidase substrates including Z-Phe-Arg-NHMec and Z-Arg-Arg-NHMec. In cells it contributes to lysosomal protein turnover and tissue homeostasis. It features a canonical papain-like catalytic fold.
Cathepsin O is a lysosomal cysteine peptidase of family C1 (papain family). The recombinant human enzyme is catalytically active at pH 6.0 and inhibited by compound E-64. It is ubiquitously expressed in human tissues, with the human gene at locus 4q31-32. The recombinant human enzyme hydrolyzes synthetic endopeptidase substrates including Z-Phe-Arg-NHMec and Z-Arg-Arg-NHMec. In cells it contributes to lysosomal protein turnover and tissue homeostasis. It features a canonical papain-like catalytic fold.
References:
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
