Coagulation factor VIIa
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.21 Serine endopeptidases > 3.4.21.21 coagulation factor VIIa
Coagulation factor VIIa is an activated serine protease in family S1 formed from factor VII precursor; the cattle enzyme is more readily inhibited by diisopropyl fluorophosphate than the human, and it selectively cleaves the Arg-Ile bond in factor X to form factor Xa. By initiating the extrinsic coagulation cascade it drives blood coagulation. It appears in viruses and cellular organisms.
Coagulation factor VIIa is an activated serine protease in family S1 formed from factor VII precursor; the cattle enzyme is more readily inhibited by diisopropyl fluorophosphate than the human, and it selectively cleaves the Arg-Ile bond in factor X to form factor Xa. By initiating the extrinsic coagulation cascade it drives blood coagulation. It appears in viruses and cellular organisms.
References:
Biomedical Dictionary
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