Costunolide synthase

Definition:

EC Tree > 1 Oxidoreductases > 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen > 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor > 1.14.14.150 costunolide synthase
Costunolide synthase is a chicory cytochrome P-450 that 6-hydroxylates germacra-1(10),4,11(13)-trien-12-oate; the 6α-hydroxy intermediate spontaneously cyclizes to the lactone ring of (+)-costunolide.

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