D-glutamate cyclase

Definition:

EC Tree > 4 Lyases > 4.2 Carbon-oxygen lyases > 4.2.1 Hydro-lyases > 4.2.1.48 D-glutamate cyclase
D-Glutamate cyclase is a lactamase/cyclase that cyclizes D-glutamate into 5-oxo-D-proline (D-pyroglutamate) and water; it also acts on various derivatives of D-glutamate. It appears in viruses and cellular organisms. Structurally it is a D-amino-acid cyclase.

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