Dihydropyrimidinase

Definition:

EC Tree > 3 Hydrolases > 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds > 3.5.2 In cyclic amides > 3.5.2.2 dihydropyrimidinase
Isatin hydrolase is a manganese-dependent hydrolase found in bacteria and eukaryotes, involved in indole-3-acetic acid degradation. It hydrolyzes isatin into isatinate. In bacteria it opens the isatin ring. It requires Mn2+.

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