Dinorphin-converting enzyme
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.22 Cysteine endopeptidases > 3.4.22.20 dinorphin-converting enzyme
Dinorphin-converting enzyme is a cysteine protease that specifically processes the opioid peptide precursor into the mature opioid peptide dynorphin at an internal cleavage site. It contributes to opioid peptide maturation in neuroendocrine tissues. In organisms it regulates pain modulation and stress responses through dynorphin generation. It features a thiol-dependent catalytic apparatus optimized for prohormone cleavage.
Dinorphin-converting enzyme is a cysteine protease that specifically processes the opioid peptide precursor into the mature opioid peptide dynorphin at an internal cleavage site. It contributes to opioid peptide maturation in neuroendocrine tissues. In organisms it regulates pain modulation and stress responses through dynorphin generation. It features a thiol-dependent catalytic apparatus optimized for prohormone cleavage.
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