DNTPase
Definition:
EC Tree > 3 Hydrolases > 3.1 Acting on ester bonds > 3.1.5 Triphosphoric-monoester hydrolases > 3.1.5.B1 dNTPase
dNTPase is a broad-specificity dNTP-hydrolysing phosphatase that hydrolyses a deoxynucleoside triphosphate into the corresponding deoxynucleotide and triphosphate. By sanitising the dNTP pool it prevents non-canonical nucleotides from being incorporated into DNA and supports genome stability. It is distributed across Eukaryota and Bacteria and adopts a dNTP-pyrophosphatase fold.
dNTPase is a broad-specificity dNTP-hydrolysing phosphatase that hydrolyses a deoxynucleoside triphosphate into the corresponding deoxynucleotide and triphosphate. By sanitising the dNTP pool it prevents non-canonical nucleotides from being incorporated into DNA and supports genome stability. It is distributed across Eukaryota and Bacteria and adopts a dNTP-pyrophosphatase fold.
References:
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