Endonuclease Bax1
Definition:
EC Tree > 3 Hydrolases > 3.1 Acting on ester bonds > > 3.1.99.B6 endonuclease Bax1
Endonuclease Bax1 is a structure-specific endonuclease from Thermoplasma acidophilum that recognises DNA carrying a 3' overhang and specifically incises the single-stranded region 4–6 nucleotides away from the single-stranded/double-stranded junction, acting as a structure-specific rather than sequence-specific endonuclease. By processing branched and 3'-overhang DNA it supports archaeal nucleotide-excision-like repair and replication restart. It contains an XPF-like nuclease domain.
Endonuclease Bax1 is a structure-specific endonuclease from Thermoplasma acidophilum that recognises DNA carrying a 3' overhang and specifically incises the single-stranded region 4–6 nucleotides away from the single-stranded/double-stranded junction, acting as a structure-specific rather than sequence-specific endonuclease. By processing branched and 3'-overhang DNA it supports archaeal nucleotide-excision-like repair and replication restart. It contains an XPF-like nuclease domain.
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