Endothelin-converting enzyme 1
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.24 Metalloendopeptidases > 3.4.24.71 endothelin-converting enzyme 1
Fibrolase is a 23-kDa non-hemorrhagic zinc metalloendopeptidase from the southern copperhead snake (Agkistrodon contortrix contortrix) venom, in peptidase family M12. It hydrolyzes -Ala14-/-Leu- in the insulin B chain and -Lys413-/-Leu- in the Aalpha chain of fibrinogen. In venom it defibrinogenates prey. It features an M12-family zinc catalytic domain.
Fibrolase is a 23-kDa non-hemorrhagic zinc metalloendopeptidase from the southern copperhead snake (Agkistrodon contortrix contortrix) venom, in peptidase family M12. It hydrolyzes -Ala14-/-Leu- in the insulin B chain and -Lys413-/-Leu- in the Aalpha chain of fibrinogen. In venom it defibrinogenates prey. It features an M12-family zinc catalytic domain.
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