Enterobacter ribonuclease
Definition:
EC Tree > 4 Lyases > 4.6 Phosphorus-oxygen lyases > 4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date) > 4.6.1.21 Enterobacter ribonuclease
Enterobacter ribonuclease prefers cleavage at Cp-A bonds; homopolymers of A, U or G are not hydrolyzed, CpG is hydrolyzed less well, and there is no detectable hydrolysis between two purines or two pyrimidines. The two-step endonucleolytic cleavage first produces 2',3'-cyclic phosphodiester-ended oligonucleotides, which are subsequently hydrolyzed to 3'-phosphates. Structurally it is an Enterobacteriaceae-specific RNase.
Enterobacter ribonuclease prefers cleavage at Cp-A bonds; homopolymers of A, U or G are not hydrolyzed, CpG is hydrolyzed less well, and there is no detectable hydrolysis between two purines or two pyrimidines. The two-step endonucleolytic cleavage first produces 2',3'-cyclic phosphodiester-ended oligonucleotides, which are subsequently hydrolyzed to 3'-phosphates. Structurally it is an Enterobacteriaceae-specific RNase.
References:
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
